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The modelling of infectious disease spread at the multi-host level (epidemiology) has garnered a lot of attention, and has attracted a large community of researchers with significant, dedicated funding programmes. In contrast, the community of researchers working on models of disease spread at the single cell, cell culture, organ or single-host level (virology, immunology), an equally important and complementary aspect of disease control and eradication, is much smaller, and distributed around the world. Nonetheless, several of us are working on related problems and have benefited significantly from the 1st Workshop on Virus Dynamics which was held in Summer 2013 in Frankfurt, Germany.

The objective of this year's 2-day workshop is to build on the success of the 1st workshop and to further discuss the present state and future development in modelling virus dynamics from the single-cell level up to the level of a single host. Participants will discuss their progress in developing optimal experimental systems plus mathematical and computational modelling platforms which, when combined, enable them to extract the key parameters characterizing viral replication in vitro or in vivo. The topics covered at this year's workshop will include the comparison of local virus spread via direct, cell-to-cell transfer versus distal spread by release and diffusion of free virions, the effect of stochasticity at low virus concentration during early infection and its possible long-term impact on progress of infection, the emergence and growth kinetics of defective interfering particles and the artifacts it could introduce in commonly used experimental systems, and the role of host and immune factors in controlling or arresting the infection.